Immune boosting benefits of strain-specific probiotics

Immune boosting benefits of strain-specific probiotics

Jun 18, 2021


Our immune system is a complex network of cells, tissues, and organs such as white blood cells, antibodies, the lymphatic system, the spleen and etc.1 About 70% of the immune system is located in the gut.

Probiotics are often known as good bacteria present in the gut, which plays a vital role in modulating immune function in our body. When harmful bacteria overgrowth in the gut, it can affect the regulation of immune response in the body.2 The effects of probiotics in the immune system are believed to be strain-specific that work differently.3.4.

Studies showed that L. acidophilus NCFM® treated group has significant
lower no of episode of fever (p<0.01)*, cough (p< 0.05)** and
antibiotics use (p<0.001)*** compare to placebo group

L. acidophilus NCFM® is one of the most clinically researched probiotics strains that has many benefits, including boosting the body’s immune system and restricting pathogens’ growth. L. acidophilus NCFM® supplementation among children aged 3 to 5 years old has been shown to help decrease the episode of influenza-like symptoms such as fever, coughing and reduce the usage of antibiotics5. Children can get flu more often than an adult. Supplementation with probiotics such as L. acidophilusNCFM® is helpful in reducing the incidence and shortening the duration of sickness, the duration of having fever, coughing and runny nose significantly decreased by 32%.5

Serum IgG level increase significantly (p<0.05)*
compare with placebo group between D0 and D21

Serum IgA & IgM level increase significantly (p<0.05)*
compare with placebo group between D21 and D28

Besides L. acidophilus NCFM® , strain-specific probiotics such as B. lactis BL-04 also can help to boost body immunity by stimulating the body to produce antibodies. Antibodies (also known as immunoglobulins) are produced by white blood cells to help our body fight against pathogens such as harmful bacteria and virus infections. Both probiotics have been shown to increase body antibody, L. acidophilus NCFM® increases antibody IgA and IgM while B. lactis BL-04 increases the production of antibody IgG6.

Find more about MEGA BiO-LiFE product containing L. acidophilus NCFM®

  1. Betterhealthchannel, 2017. Immune system explained. Retrieved 5 June, 2021 from
  2. Wu, H-J., Wu, E., 2012. The role of gut microbiota in immune homeostasis and autoimmunity. Gut Microbes., 3(1): 4–14
  3. Yana, F., and Polk, D.B., 2011. Probiotics and immune health. Current opinion in gastroenterology, 27(6), 496–501
  4. Underwood, M.A., 2016. Probiotics and Innate and Adaptive Immune Responses in Premature Infants. Forum on immunopathological diseases and therapeutics, 7(1-2), 1–15
  5. Leyer, G.J., Li, S., Mubasher, M.E., Reifer, C., and Ouwehand, A.C., 2009. Probiotic effects on cold and influenza-like symptom incidence and duration in children. Pediatrics, 124(2):e172-179